Journal: Micromachines
Article Title: Rapid Detection and Trapping of Extracellular Vesicles by Electrokinetic Concentration for Liquid Biopsy on Chip
doi: 10.3390/mi9060306
Figure Lengend Snippet: Captured extracellular vesicles on a superaldehyde glass based on surface binding after preconcentration at 45 V/cm for 30 min. ( a ) Electrokinetic preconcentration of extracellular vesicles in the microchannel, ( b ) The two white arrows and the black dotted square in the SEM image indicated areas of captured extracellular vesicles on a superaldehyde substrate after preconcentration. The SEM inset shows aggregated EVs with a size of <~200 nm.
Article Snippet: To demonstrate this flexibility of interfacing witha variety of substrates, we also used superaldehyde glass substrate (Arrayit) as well as plain glass slide with 3D-printed microtraps to passively trap extracellular vesicles near the ion-selective membrane during ICP at 45 V/cm within 30 min.
Techniques: Binding Assay